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Synaptic Protein Degradation Controls Sexually Dimorphic Circuits through Regulation of DCC/UNC-40

Sexually dimorphic circuits underlie behavioral differences between the sexes, yet the molecular mechanisms involved in their formation are poorly understood. We show here that sexually dimorphic connectivity patterns arise in C. elegans through local ubiquitin-mediated protein degradation in select...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Curr Biol
Egile Nagusiak: Salzberg, Yehuda, Pechuk, Vladyslava, Gat, Asaf, Setty, Hagar, Sela, Sapir, Oren-Suissa, Meital
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cell Press 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658809/
https://ncbi.nlm.nih.gov/pubmed/32857970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2020.08.002
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