UNC-6 (netrin) stabilizes oscillatory clustering of the UNC-40 (DCC) receptor to orient polarity

The receptor deleted in colorectal cancer (DCC) directs dynamic polarizing activities in animals toward its extracellular ligand netrin. How DCC polarizes toward netrin is poorly understood. By performing live-cell imaging of the DCC orthologue UNC-40 during anchor cell invasion in Caenorhabditis el...

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Autors principals: Wang, Zheng, Linden, Lara M., Naegeli, Kaleb M., Ziel, Joshua W., Chi, Qiuyi, Hagedorn, Elliott J., Savage, Natasha S., Sherwood, David R.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2014
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151141/
https://ncbi.nlm.nih.gov/pubmed/25154398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201405026
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