UNC-6 (netrin) stabilizes oscillatory clustering of the UNC-40 (DCC) receptor to orient polarity

The receptor deleted in colorectal cancer (DCC) directs dynamic polarizing activities in animals toward its extracellular ligand netrin. How DCC polarizes toward netrin is poorly understood. By performing live-cell imaging of the DCC orthologue UNC-40 during anchor cell invasion in Caenorhabditis el...

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Detalhes bibliográficos
Main Authors: Wang, Zheng, Linden, Lara M., Naegeli, Kaleb M., Ziel, Joshua W., Chi, Qiuyi, Hagedorn, Elliott J., Savage, Natasha S., Sherwood, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151141/
https://ncbi.nlm.nih.gov/pubmed/25154398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201405026
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