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UNC-6 (netrin) stabilizes oscillatory clustering of the UNC-40 (DCC) receptor to orient polarity

The receptor deleted in colorectal cancer (DCC) directs dynamic polarizing activities in animals toward its extracellular ligand netrin. How DCC polarizes toward netrin is poorly understood. By performing live-cell imaging of the DCC orthologue UNC-40 during anchor cell invasion in Caenorhabditis el...

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Détails bibliographiques
Auteurs principaux: Wang, Zheng, Linden, Lara M., Naegeli, Kaleb M., Ziel, Joshua W., Chi, Qiuyi, Hagedorn, Elliott J., Savage, Natasha S., Sherwood, David R.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151141/
https://ncbi.nlm.nih.gov/pubmed/25154398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201405026
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