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Synaptic Protein Degradation Controls Sexually Dimorphic Circuits through Regulation of DCC/UNC-40

Sexually dimorphic circuits underlie behavioral differences between the sexes, yet the molecular mechanisms involved in their formation are poorly understood. We show here that sexually dimorphic connectivity patterns arise in C. elegans through local ubiquitin-mediated protein degradation in select...

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Bibliografiske detaljer
Udgivet i:Curr Biol
Main Authors: Salzberg, Yehuda, Pechuk, Vladyslava, Gat, Asaf, Setty, Hagar, Sela, Sapir, Oren-Suissa, Meital
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658809/
https://ncbi.nlm.nih.gov/pubmed/32857970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2020.08.002
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