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Synaptic Protein Degradation Controls Sexually Dimorphic Circuits through Regulation of DCC/UNC-40

Sexually dimorphic circuits underlie behavioral differences between the sexes, yet the molecular mechanisms involved in their formation are poorly understood. We show here that sexually dimorphic connectivity patterns arise in C. elegans through local ubiquitin-mediated protein degradation in select...

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Detalhes bibliográficos
Publicado no:Curr Biol
Main Authors: Salzberg, Yehuda, Pechuk, Vladyslava, Gat, Asaf, Setty, Hagar, Sela, Sapir, Oren-Suissa, Meital
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658809/
https://ncbi.nlm.nih.gov/pubmed/32857970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2020.08.002
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