Population Pharmacokinetic–Pharmacodynamic Relationships of Sarilumab Using Disease Activity Score 28-Joint C-Reactive Protein and Absolute Neutrophil Counts in Patients with Rheumatoid Arthritis

BACKGROUND: Sarilumab is a human monoclonal antibody blocking the interleukin-6 receptor alpha (IL-6Rɑ) approved for the treatment of moderately to severely active rheumatoid arthritis in adults with inadequate response or intolerance to other disease-modifying antirheumatic drugs. OBJECTIVE: The ai...

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Udgivet i:Clin Pharmacokinet
Main Authors: Ma, Lei, Xu, Christine, Paccaly, Anne, Kanamaluru, Vanaja
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2020
Fag:
Original Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658085/
https://ncbi.nlm.nih.gov/pubmed/32451909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-020-00899-7
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