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Population Pharmacokinetics of Sarilumab in Patients with Rheumatoid Arthritis
BACKGROUND AND OBJECTIVE: Sarilumab binds to the interleukin-6 receptor with high affinity, inhibiting cis and trans signaling by interleukin-6. Sarilumab has demonstrated efficacy and safety in patients with rheumatoid arthritis. The objective of this study was to develop a population-pharmacokinet...
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| Publicado no: | Clin Pharmacokinet |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6856490/ https://ncbi.nlm.nih.gov/pubmed/31055792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-019-00765-1 |
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