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Development of a Physiologically-Based Pharmacokinetic Model for Ocular Disposition of Monoclonal Antibodies in Rabbits

Development of protein therapeutics for ocular disorders, particularly age-related macular degeneration (AMD), is a highly competitive and expanding therapeutic area. However, the application of a predictive and translatable ocular PK model to better understand ocular disposition of protein therapeu...

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Bibliografiske detaljer
Udgivet i:J Pharmacokinet Pharmacodyn
Main Authors: Bussing, David, Shah, Dhaval K
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658046/
https://ncbi.nlm.nih.gov/pubmed/32876799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-020-09713-0
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