Understanding the neuroprotective effect of tranexamic acid: an exploratory analysis of the CRASH-3 randomised trial

BACKGROUND: The CRASH-3 trial hypothesised that timely tranexamic acid (TXA) treatment might reduce deaths from intracranial bleeding after traumatic brain injury (TBI). To explore the mechanism of action of TXA in TBI, we examined the timing of its effect on death. METHODS: The CRASH-3 trial random...

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Detalles Bibliográficos
Publicado en:Crit Care
Main Authors: Brenner, Amy, Belli, Antonio, Chaudhri, Rizwana, Coats, Timothy, Frimley, Lauren, Jamaluddin, Sabariah Faizah, Jooma, Rashid, Mansukhani, Raoul, Sandercock, Peter, Shakur-Still, Haleema, Shokunbi, Temitayo, Roberts, Ian
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657351/
https://ncbi.nlm.nih.gov/pubmed/33172504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-020-03243-4
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