Understanding the neuroprotective effect of tranexamic acid: an exploratory analysis of the CRASH-3 randomised trial

BACKGROUND: The CRASH-3 trial hypothesised that timely tranexamic acid (TXA) treatment might reduce deaths from intracranial bleeding after traumatic brain injury (TBI). To explore the mechanism of action of TXA in TBI, we examined the timing of its effect on death. METHODS: The CRASH-3 trial random...

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Bibliografische gegevens
Gepubliceerd in:Crit Care
Hoofdauteurs: Brenner, Amy, Belli, Antonio, Chaudhri, Rizwana, Coats, Timothy, Frimley, Lauren, Jamaluddin, Sabariah Faizah, Jooma, Rashid, Mansukhani, Raoul, Sandercock, Peter, Shakur-Still, Haleema, Shokunbi, Temitayo, Roberts, Ian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2020
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657351/
https://ncbi.nlm.nih.gov/pubmed/33172504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-020-03243-4
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