Understanding the neuroprotective effect of tranexamic acid: an exploratory analysis of the CRASH-3 randomised trial

BACKGROUND: The CRASH-3 trial hypothesised that timely tranexamic acid (TXA) treatment might reduce deaths from intracranial bleeding after traumatic brain injury (TBI). To explore the mechanism of action of TXA in TBI, we examined the timing of its effect on death. METHODS: The CRASH-3 trial random...

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Dettagli Bibliografici
Pubblicato in:Crit Care
Autori principali: Brenner, Amy, Belli, Antonio, Chaudhri, Rizwana, Coats, Timothy, Frimley, Lauren, Jamaluddin, Sabariah Faizah, Jooma, Rashid, Mansukhani, Raoul, Sandercock, Peter, Shakur-Still, Haleema, Shokunbi, Temitayo, Roberts, Ian
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657351/
https://ncbi.nlm.nih.gov/pubmed/33172504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-020-03243-4
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