Accuracy of time to treatment estimates in the CRASH-3 clinical trial: impact on the trial results

BACKGROUND: Early treatment with tranexamic acid may reduce deaths after traumatic brain injury (TBI). In mild and moderate TBI, there is a time to treatment interaction, with early treatment being most beneficial. Time to treatment was recorded by clinicians and is subject to error. Using monitorin...

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Vydáno v:Trials
Hlavní autoři: Mansukhani, Raoul, Frimley, Lauren, Shakur-Still, Haleema, Sharples, Linda, Roberts, Ian
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7382791/
https://ncbi.nlm.nih.gov/pubmed/32711551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-020-04623-5
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