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Novel MEK inhibitor trametinib and other retinoblastoma gene (RB)‐reactivating agents enhance efficacy of 5‐fluorouracil on human colon cancer cells
Chemotherapy for colorectal cancer has become more complicated and diversified with the appearance of molecular‐targeting agents. 5‐Fluorouracil (5‐FU) has been a mainstay of chemotherapy for colorectal cancer, but it is still unknown whether the combining of 5‐FU with novel molecular‐targeting agen...
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| Publicado en: | Cancer Sci |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7657192/ https://ncbi.nlm.nih.gov/pubmed/23438367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12139 |
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