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Aurora B inhibitor barasertib and cytarabine exert a greater‐than‐additive cytotoxicity in acute myeloid leukemia cells

Barasertib, an aurora B inhibitor, terminates cell division, introduces polyploidy, and consequently causes apoptosis. In the present study, we evaluated the effect of the combination of barasertib and cytarabine (ara‐C), a key agent for leukemia chemotherapy, on leukemic cells in vitro. Human leuke...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cancer Sci
Päätekijät: Yamauchi, Takahiro, Uzui, Kanako, Shigemi, Hiroko, Negoro, Eiju, Yoshida, Akira, Ueda, Takanori
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657165/
https://ncbi.nlm.nih.gov/pubmed/23557198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12164
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