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Aurora B inhibitor barasertib and cytarabine exert a greater‐than‐additive cytotoxicity in acute myeloid leukemia cells
Barasertib, an aurora B inhibitor, terminates cell division, introduces polyploidy, and consequently causes apoptosis. In the present study, we evaluated the effect of the combination of barasertib and cytarabine (ara‐C), a key agent for leukemia chemotherapy, on leukemic cells in vitro. Human leuke...
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| Publicado no: | Cancer Sci |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7657165/ https://ncbi.nlm.nih.gov/pubmed/23557198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12164 |
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