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CrrB Positively Regulates High-Level Polymyxin Resistance and Virulence in Klebsiella pneumoniae
Polymyxin resistance (PR) threatens the treatment of carbapenem-resistant Klebsiella pneumoniae (CRKP) infections. PR frequently arises through chemical modification of the lipid A portion of lipopolysaccharide. Various mutations are implicated in PR, including in three two-component systems—CrrA/B,...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7656232/ https://ncbi.nlm.nih.gov/pubmed/33113377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108313 |
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