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Amino Acid Substitutions of CrrB Responsible for Resistance to Colistin through CrrC in Klebsiella pneumoniae

Colistin is a last-resort antibiotic for treatment of carbapenem-resistant Klebsiella pneumoniae. A recent study indicated that missense mutations in the CrrB protein contribute to colistin resistance. In our previous study, mechanisms of colistin resistance were defined in 17 of 26 colistin-resista...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Cheng, Yi-Hsiang, Lin, Tzu-Lung, Lin, Yi-Tsung, Wang, Jin-Town
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879426/
https://ncbi.nlm.nih.gov/pubmed/27067316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00009-16
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