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Considerations for achieving maximized DNA recovery in solid-phase DNA-encoded library synthesis

DNA-encoded library (DEL) technology enables rapid, economical synthesis and exploration of novel chemical space. Reaction development for DEL synthesis has recently accelerated in pace with a specific emphasis on ensuring that the reaction does not compromise the integrity of the encoding DNA. Howe...

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Publié dans:ACS Comb Sci
Auteurs principaux: Price, Alexander K., Paegel, Brian M.
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7655546/
https://ncbi.nlm.nih.gov/pubmed/32786319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscombsci.0c00101
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