A Solution Phase Platform to Characterize Chemical Reaction Compatibility with DNA-Encoded Chemical Library Synthesis

DNA-Encoded Chemical Library (DECL) synthesis must occur in aqueous media under conditions that preserve the integrity of the DNA encoding tag. While the identification of “DNA-compatible” reaction conditions is critical for the development of DECL designs that explore previously inaccessible chemic...

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Vydáno v:ACS Comb Sci
Hlavní autoři: Ratnayake, Anokha S., Flanagan, Mark E., Foley, Timothy L., Smith, Justin D., Johnson, Jillian G., Bellenger, Justin, Montgomery, Justin I., Paegel, Brian M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938256/
https://ncbi.nlm.nih.gov/pubmed/31425646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscombsci.9b00113
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