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Effects of an allosteric hemoglobin affinity modulator on arterial blood gases and cardiopulmonary responses during normoxic and hypoxic low-intensity exercise

Numerous pathophysiological conditions induce hypoxemia-related cardiopulmonary perturbations, decrements in exercise capacity, and debilitating symptoms. Accordingly, this study investigated the efficacy of an allosteric hemoglobin modulator (voxelotor) to enhance arterial oxygen saturation during...

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Veröffentlicht in:J Appl Physiol (1985)
Hauptverfasser: Stewart, Glenn M., Chase, Steven, Cross, Troy J., Wheatley-Guy, Courtney M., Joyner, Michael J., Curry, Timothy, Lehrer-Graiwer, Josh, Dufu, Kobina, Vlahakis, Nicholas E., Johnson, Bruce D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654636/
https://ncbi.nlm.nih.gov/pubmed/32324473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00185.2019
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