Characterization of Novel Cross-Reactive Influenza B Virus Hemagglutinin Head Specific Antibodies That Lack Hemagglutination Inhibition Activity

Humoral immune responses to influenza virus vaccines in elderly individuals are poorly adapted toward new antigenically drifted influenza virus strains. Instead, older individuals respond in an original antigenic sin fashion and produce much more cross-reactive but less potent antibodies. Here, we i...

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Vydáno v:J Virol
Hlavní autoři: Kirkpatrick, Ericka, Henry, Carole, McMahon, Meagan, Jiang, Kaijun, Strohmeier, Shirin, van Bakel, Harm, Wilson, Patrick C., Krammer, Florian
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654279/
https://ncbi.nlm.nih.gov/pubmed/32907980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01185-20
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