Characterization of Novel Cross-Reactive Influenza B Virus Hemagglutinin Head Specific Antibodies That Lack Hemagglutination Inhibition Activity

Humoral immune responses to influenza virus vaccines in elderly individuals are poorly adapted toward new antigenically drifted influenza virus strains. Instead, older individuals respond in an original antigenic sin fashion and produce much more cross-reactive but less potent antibodies. Here, we i...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Kirkpatrick, Ericka, Henry, Carole, McMahon, Meagan, Jiang, Kaijun, Strohmeier, Shirin, van Bakel, Harm, Wilson, Patrick C., Krammer, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654279/
https://ncbi.nlm.nih.gov/pubmed/32907980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01185-20
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