Characterization of Novel Cross-Reactive Influenza B Virus Hemagglutinin Head Specific Antibodies That Lack Hemagglutination Inhibition Activity

Humoral immune responses to influenza virus vaccines in elderly individuals are poorly adapted toward new antigenically drifted influenza virus strains. Instead, older individuals respond in an original antigenic sin fashion and produce much more cross-reactive but less potent antibodies. Here, we i...

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Publicado en:J Virol
Autores principales: Kirkpatrick, Ericka, Henry, Carole, McMahon, Meagan, Jiang, Kaijun, Strohmeier, Shirin, van Bakel, Harm, Wilson, Patrick C., Krammer, Florian
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2020
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654279/
https://ncbi.nlm.nih.gov/pubmed/32907980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01185-20
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