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Female-biased effects of aging on a chimeric hemagglutinin stalk-based universal influenza virus vaccine in mice
To determine if biological sex and age intersect to affect universal influenza vaccine-induced immunity, adult and aged male and female C57BL/6 mice were sequentially immunized with a chimeric-hemagglutinin (cHA) stalk-based H1 vaccine. Adult mice developed greater quantity and quality of H1-stalk a...
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| Udgivet i: | Vaccine |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2022
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8178415/ https://ncbi.nlm.nih.gov/pubmed/33293159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2020.11.057 |
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