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Broad-Spectrum Antiviral Entry Inhibition by Interfacially Active Peptides

Numerous peptides inhibit the entry of enveloped viruses into cells. Some of these peptides have been shown to inhibit multiple unrelated viruses. We have suggested that such broad-spectrum antiviral peptides share a property called interfacial activity; they are somewhat hydrophobic and amphipathic...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Hoffmann, Andrew R., Guha, Shantanu, Wu, Eric, Ghimire, Jenisha, Wang, Yilin, He, Jing, Garry, Robert F., Wimley, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654261/
https://ncbi.nlm.nih.gov/pubmed/32907984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01682-20
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