Broad-Spectrum Antiviral Entry Inhibition by Interfacially Active Peptides

Numerous peptides inhibit the entry of enveloped viruses into cells. Some of these peptides have been shown to inhibit multiple unrelated viruses. We have suggested that such broad-spectrum antiviral peptides share a property called interfacial activity; they are somewhat hydrophobic and amphipathic...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Hoffmann, Andrew R., Guha, Shantanu, Wu, Eric, Ghimire, Jenisha, Wang, Yilin, He, Jing, Garry, Robert F., Wimley, William C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2020
Materias:
Structure and Assembly
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654261/
https://ncbi.nlm.nih.gov/pubmed/32907984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01682-20
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