Broad-Spectrum Antiviral Entry Inhibition by Interfacially Active Peptides

Numerous peptides inhibit the entry of enveloped viruses into cells. Some of these peptides have been shown to inhibit multiple unrelated viruses. We have suggested that such broad-spectrum antiviral peptides share a property called interfacial activity; they are somewhat hydrophobic and amphipathic...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Hoffmann, Andrew R., Guha, Shantanu, Wu, Eric, Ghimire, Jenisha, Wang, Yilin, He, Jing, Garry, Robert F., Wimley, William C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Structure and Assembly
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654261/
https://ncbi.nlm.nih.gov/pubmed/32907984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01682-20
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