Genetic and epigenetic landscape of IDH-wildtype glioblastomas with FGFR3-TACC3 fusions

A subset of glioblastomas (GBMs) harbors potentially druggable oncogenic FGFR3-TACC3 (F3T3) fusions. However, their associated molecular and clinical features are poorly understood. Here we analyze the frequency of F3T3-fusion positivity, its associated genetic and methylation profiles, and its impa...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Acta Neuropathol Commun
Egile Nagusiak: Mata, Douglas A., Benhamida, Jamal K., Lin, Andrew L., Vanderbilt, Chad M., Yang, Soo-Ryum, Villafania, Liliana B., Ferguson, Donna C., Jonsson, Philip, Miller, Alexandra M., Tabar, Viviane, Brennan, Cameron W., Moss, Nelson S., Sill, Martin, Benayed, Ryma, Mellinghoff, Ingo K., Rosenblum, Marc K., Arcila, Maria E., Ladanyi, Marc, Bale, Tejus A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2020
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653727/
https://ncbi.nlm.nih.gov/pubmed/33168106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-01058-6
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