Genetic and epigenetic landscape of IDH-wildtype glioblastomas with FGFR3-TACC3 fusions

A subset of glioblastomas (GBMs) harbors potentially druggable oncogenic FGFR3-TACC3 (F3T3) fusions. However, their associated molecular and clinical features are poorly understood. Here we analyze the frequency of F3T3-fusion positivity, its associated genetic and methylation profiles, and its impa...

Full description

Saved in:
Bibliographic Details
Published in:Acta Neuropathol Commun
Main Authors: Mata, Douglas A., Benhamida, Jamal K., Lin, Andrew L., Vanderbilt, Chad M., Yang, Soo-Ryum, Villafania, Liliana B., Ferguson, Donna C., Jonsson, Philip, Miller, Alexandra M., Tabar, Viviane, Brennan, Cameron W., Moss, Nelson S., Sill, Martin, Benayed, Ryma, Mellinghoff, Ingo K., Rosenblum, Marc K., Arcila, Maria E., Ladanyi, Marc, Bale, Tejus A.
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653727/
https://ncbi.nlm.nih.gov/pubmed/33168106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-01058-6
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items