Diabetic phenotype in mouse and humans reduces the number of microglia around β-amyloid plaques

BACKGROUND: Alzheimer’s disease (AD) is the most common neurodegenerative disease and type 2 diabetes (T2D) plays an important role in conferring the risk for AD. Although AD and T2D share common features, the common molecular mechanisms underlying these two diseases remain elusive. METHODS: Mice wi...

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Publicado en:Mol Neurodegener
Autores principales: Natunen, Teemu, Martiskainen, Henna, Marttinen, Mikael, Gabbouj, Sami, Koivisto, Hennariikka, Kemppainen, Susanna, Kaipainen, Satu, Takalo, Mari, Svobodová, Helena, Leppänen, Luukas, Kemiläinen, Benjam, Ryhänen, Simo, Kuulasmaa, Teemu, Rahunen, Eija, Juutinen, Sisko, Mäkinen, Petra, Miettinen, Pasi, Rauramaa, Tuomas, Pihlajamäki, Jussi, Haapasalo, Annakaisa, Leinonen, Ville, Tanila, Heikki, Hiltunen, Mikko
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653710/
https://ncbi.nlm.nih.gov/pubmed/33168021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-020-00415-2
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