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The efficiency of insulin production and its content in insulin-expressing model β-cells correlate with their Zn(2+) levels
Insulin is produced and stored inside the pancreatic β-cell secretory granules, where it is assumed to form Zn(2+)-stabilized oligomers. However, the actual storage forms of this hormone and the impact of zinc ions on insulin production in vivo are not known. Our initial X-ray fluorescence experimen...
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| Pubblicato in: | Open Biol |
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| Autori principali: | , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Royal Society
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7653362/ https://ncbi.nlm.nih.gov/pubmed/33081637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.200137 |
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