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Reprogramming of human cells to pluripotency induces CENP-A chromatin depletion
Pluripotent stem cells (PSCs) are central to development as they are the precursors of all cell types in the embryo. Therefore, maintaining a stable karyotype is essential, both for their physiological role as well as for their use in regenerative medicine. Karyotype abnormalities in PSCs in culture...
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| Publicado no: | Open Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7653353/ https://ncbi.nlm.nih.gov/pubmed/33081635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.200227 |
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