Dynamically reorganized chromatin is the key for the reprogramming of somatic cells to pluripotent cells

Nucleosome positioning and histone modification play a critical role in gene regulation, but their role during reprogramming has not been fully elucidated. Here, we determined the genome-wide nucleosome coverage and histone methylation occupancy in mouse embryonic fibroblasts (MEFs), induced pluripo...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Huang, Kaimeng, Zhang, Xiaobai, Shi, Jiejun, Yao, Mingze, Lin, Jiannan, Li, Jiao, Liu, He, Li, Huanhuan, Shi, Guang, Wang, Zhibin, Zhang, Biliang, Chen, Jiekai, Pan, Guangjin, Jiang, Cizhong, Pei, Duanqing, Yao, Hongjie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671053/
https://ncbi.nlm.nih.gov/pubmed/26639176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17691
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