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The nuclear factor CECR2 promotes somatic cell reprogramming by reorganizing the chromatin structure

Somatic cells can be reprogrammed into pluripotent stem cells with a minimal set of defined factors, Oct3/4, Sox2, Klf4, and c-Myc, also known as OKSM, although this reprogramming is somewhat inefficient. Recent work has identified other nuclear factors, including SALL4, that can synergize with the...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Wu, Linlin, Zhao, Guoqing, Xu, Shuyang, Kuang, Junqi, Ming, Jin, Wu, Guangmin, Wang, Tao, Wang, Bo, Zhu, Ping, Pei, Duanqing, Liu, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948406/
https://ncbi.nlm.nih.gov/pubmed/33144328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014598
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