Mitochondrial DNA Mutation Analysis in Breast Cancer: Shifting From Germline Heteroplasmy Toward Homoplasmy in Tumors

Studies have suggested a potential role of somatic mitochondrial mutations in cancer development. To analyze the landscape of somatic mitochondrial mutation in breast cancer and to determine whether mitochondrial DNA (mtDNA) mutational burden is correlated with overall survival (OS), we sequenced wh...

詳細記述

保存先:
書誌詳細
出版年:Front Oncol
主要な著者: Pérez-Amado, Carlos Jhovani, Tovar, Hugo, Gómez-Romero, Laura, Beltrán-Anaya, Fredy Omar, Bautista-Piña, Verónica, Dominguez-Reyes, Carlos, Villegas-Carlos, Felipe, Tenorio-Torres, Alberto, Alfaro-Ruíz, Luis Alberto, Hidalgo-Miranda, Alfredo, Jiménez-Morales, Silvia
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2020
主題:
Oncology
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653098/
https://ncbi.nlm.nih.gov/pubmed/33194675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.572954
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