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Impact of Biological Sex on Immune Activation and Frequency of the Latent HIV Reservoir During Suppressive Antiretroviral Therapy

BACKGROUND: Persistent HIV infection of long-lived resting CD4 T cells, despite antiretroviral therapy (ART), remains a barrier to HIV cure. Women have a more robust type 1 interferon response during HIV infection relative to men, contributing to lower initial plasma viremia. As lower viremia during...

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Bibliografiske detaljer
Udgivet i:J Infect Dis
Main Authors: Falcinelli, Shane D, Shook-Sa, Bonnie E, Dewey, Morgan G, Sridhar, Sumati, Read, Jenna, Kirchherr, Jennifer, James, Katherine S, Allard, Brigitte, Ghofrani, Simon, Stuelke, Erin, Baker, Caroline, Roan, Nadia R, Eron, Joseph J, Kuruc, JoAnn D, Ramirez, Catalina, Gay, Cynthia, Mollan, Katie R, Margolis, David M, Adimora, Adaora A, Archin, Nancie M
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653086/
https://ncbi.nlm.nih.gov/pubmed/32496542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiaa298
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