Impact of Biological Sex on Immune Activation and Frequency of the Latent HIV Reservoir During Suppressive Antiretroviral Therapy

BACKGROUND: Persistent HIV infection of long-lived resting CD4 T cells, despite antiretroviral therapy (ART), remains a barrier to HIV cure. Women have a more robust type 1 interferon response during HIV infection relative to men, contributing to lower initial plasma viremia. As lower viremia during...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Falcinelli, Shane D, Shook-Sa, Bonnie E, Dewey, Morgan G, Sridhar, Sumati, Read, Jenna, Kirchherr, Jennifer, James, Katherine S, Allard, Brigitte, Ghofrani, Simon, Stuelke, Erin, Baker, Caroline, Roan, Nadia R, Eron, Joseph J, Kuruc, JoAnn D, Ramirez, Catalina, Gay, Cynthia, Mollan, Katie R, Margolis, David M, Adimora, Adaora A, Archin, Nancie M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653086/
https://ncbi.nlm.nih.gov/pubmed/32496542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiaa298
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