Wwox Deficiency Causes Downregulation of Prosurvival ERK Signaling and Abnormal Homeostatic Responses in Mouse Skin

Deficiency of tumor suppressor WW domain-containing oxidoreductase (WWOX) in humans and animals leads to growth retardation and premature death during postnatal developmental stages. Skin integrity is essential for organism survival due to its protection against dehydration and hypothermia. Our prev...

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Vydáno v:Front Cell Dev Biol
Hlavní autoři: Chou, Ying-Tsen, Lai, Feng-Jie, Chang, Nan-Shan, Hsu, Li-Jin
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Cell and Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7652735/
https://ncbi.nlm.nih.gov/pubmed/33195192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.558432
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