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Regulation of cell signaling and apoptosis by tumor suppressor WWOX

Human fragile WWOX gene encodes a tumor suppressor WW domain-containing oxidoreductase (named WWOX, FOR, or WOX1). Functional suppression of WWOX prevents apoptotic cell death induced by a variety of stress stimuli, such as tumor necrosis factor, UV radiation, and chemotherapeutic drug treatment. Lo...

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Bibliografski detalji
Izdano u:Exp Biol Med (Maywood)
Glavni autori: Lo, Jui-Yen, Chou, Ying-Tsen, Lai, Feng-Jie, Hsu, Li-Jin
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935227/
https://ncbi.nlm.nih.gov/pubmed/25595191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370214566747
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