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Wwox Deficiency Causes Downregulation of Prosurvival ERK Signaling and Abnormal Homeostatic Responses in Mouse Skin

Deficiency of tumor suppressor WW domain-containing oxidoreductase (WWOX) in humans and animals leads to growth retardation and premature death during postnatal developmental stages. Skin integrity is essential for organism survival due to its protection against dehydration and hypothermia. Our prev...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Chou, Ying-Tsen, Lai, Feng-Jie, Chang, Nan-Shan, Hsu, Li-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7652735/
https://ncbi.nlm.nih.gov/pubmed/33195192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.558432
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