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Wwox Deficiency Causes Downregulation of Prosurvival ERK Signaling and Abnormal Homeostatic Responses in Mouse Skin

Deficiency of tumor suppressor WW domain-containing oxidoreductase (WWOX) in humans and animals leads to growth retardation and premature death during postnatal developmental stages. Skin integrity is essential for organism survival due to its protection against dehydration and hypothermia. Our prev...

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Detalles Bibliográficos
Publicado en:Front Cell Dev Biol
Autores principales: Chou, Ying-Tsen, Lai, Feng-Jie, Chang, Nan-Shan, Hsu, Li-Jin
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7652735/
https://ncbi.nlm.nih.gov/pubmed/33195192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.558432
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