Wwox deficiency leads to neurodevelopmental and degenerative neuropathies and glycogen synthase kinase 3β-mediated epileptic seizure activity in mice

Human WWOX gene resides in the chromosomal common fragile site FRA16D and encodes a tumor suppressor WW domain-containing oxidoreductase. Loss-of-function mutations in both alleles of WWOX gene lead to autosomal recessive abnormalities in pediatric patients from consanguineous families, including mi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Acta Neuropathol Commun
Egile Nagusiak: Cheng, Ya-Yun, Chou, Ying-Tsen, Lai, Feng-Jie, Jan, Ming-Shiou, Chang, Tsung-Hao, Jou, I-Ming, Chen, Pei-Shiuan, Lo, Jui-Yen, Huang, Shiang-Suo, Chang, Nan-Shan, Liou, Yung-Tsai, Hsu, Po-Chih, Cheng, Hui-Ching, Lin, Yee-Shin, Hsu, Li-Jin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2020
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6990504/
https://ncbi.nlm.nih.gov/pubmed/32000863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-0883-3
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak