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Aberrant autophagosome formation occurs upon small molecule inhibition of ULK1 kinase activity
Autophagy is a crucial homeostatic mechanism that mediates the degradation of damaged or excess intracellular components. Such components are engulfed and sequestered into double membrane autophagosomes, which deliver their contents to lysosomes for degradation. Autophagy plays a role in numerous hu...
में बचाया:
| में प्रकाशित: | Life Sci Alliance |
|---|---|
| मुख्य लेखकों: | , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Life Science Alliance LLC
2020
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7652397/ https://ncbi.nlm.nih.gov/pubmed/33109685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202000815 |
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