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ER-Targeted Beclin 1 Supports Autophagosome Biogenesis in the Absence of ULK1 and ULK2 Kinases

Autophagy transports cytoplasmic material and organelles to lysosomes for degradation and recycling. Beclin 1 forms a complex with several other autophagy proteins and functions in the initiation phase of autophagy, but the exact role of Beclin 1 subcellular localization in autophagy initiation is s...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Anwar, Tahira, Liu, Xiaonan, Suntio, Taina, Marjamäki, Annika, Biazik, Joanna, Chan, Edmond Y. W., Varjosalo, Markku, Eskelinen, Eeva-Liisa
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562811/
https://ncbi.nlm.nih.gov/pubmed/31108943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8050475
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