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ULK1 targets Beclin-1 in autophagy
The substrates of mammalian ULK1/2 and its yeast homologue Atg1 in autophagy have remained elusive. The class III phosphatidylinositol 3-kinase component Beclin-1 has now been identified as a physiological substrate of the ULK kinases in autophagy following amino acid starvation, therefore suggestin...
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| Veröffentlicht in: | Nat Cell Biol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4442023/ https://ncbi.nlm.nih.gov/pubmed/23817237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2797 |
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