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p62/SQSTM1 droplets initiate autophagosome biogenesis and oxidative stress control
Selective autophagy contributes to the degradation of condensates, such as sequestosome 1-bodies, also called p62/SQSTM1-bodies. We showed that endogenous p62 forms gel-like structures, which serve as platforms for autophagosome formation and nuclear factor erythroid 2-related factor 2 (NRF2) activa...
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| Publicado no: | Mol Cell Oncol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8018406/ https://ncbi.nlm.nih.gov/pubmed/33855170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2021.1890990 |
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