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CHANGE-seq reveals genetic and epigenetic effects on CRISPR-Cas9 genome-wide activity
Current methods can illuminate the genome-wide activity of CRISPR-Cas9 nucleases, but are not easily scalable to the throughput needed to fully understand the principles that govern Cas9 specificity. Here we describe ‘circularization for high-throughput analysis of nuclease genome-wide effects by se...
Gorde:
| Argitaratua izan da: | Nat Biotechnol |
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| Egile Nagusiak: | , , , , , , , , , , , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7652380/ https://ncbi.nlm.nih.gov/pubmed/32541958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-020-0555-7 |
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