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STEM-16. IGF1/N-CADHERIN/b-CATENIN/CLUSTERIN SIGNALING AXIS MEDIATES ADAPTIVE RADIORESISTANCE IN GLIOBLASTOMA

Glioblastoma (GBM) is composed of heterogeneous tumor cell populations including those with stem cell properties, termed glioma stem cells (GSCs). GSCs are innately less radiation sensitive than the tumor bulk and are believed to drive GBM formation and recurrence after repeated irradiation. However...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Osuka, Satoru, Zhu, Dan, Zhang, Zhaobin, Sampetrean, Oltea, Olson, Jeffrey, Saya, Hideyuki, Van Meir, Erwin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651559/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.833
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