Integrated analysis identifies different metabolic signatures for tumor-initiating cells in a murine glioblastoma model

BACKGROUND: The metabolic preference of malignant glioma for glycolysis as an energy source is a potential therapeutic target. As a result of the cellular heterogeneity of these tumors, however, the relation between glycolytic preference, tumor formation, and tumor cell clonogenicity has remained un...

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Hlavní autoři: Saga, Isako, Shibao, Shunsuke, Okubo, Jun, Osuka, Satoru, Kobayashi, Yusuke, Yamada, Sachiko, Fujita, Satoshi, Urakami, Kenichi, Kusuhara, Masatoshi, Yoshida, Kazunari, Saya, Hideyuki, Sampetrean, Oltea
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
Basic and Translational Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096179/
https://ncbi.nlm.nih.gov/pubmed/24860177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou096
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