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Metabolic heterogeneity and plasticity of glioma stem cells in a mouse glioblastoma model

BACKGROUND: Glioblastomas have been shown to rely on glycolysis as an energy source. However, recent evidence suggests that at least a subset of glioma cells with stem cell–like properties can thrive on oxidative phosphorylation. It remains unclear whether both metabolic phenotypes support tumor pro...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Shibao, Shunsuke, Minami, Noriaki, Koike, Naoyoshi, Fukui, Nobuyuki, Yoshida, Kazunari, Saya, Hideyuki, Sampetrean, Oltea
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817950/
https://ncbi.nlm.nih.gov/pubmed/29016888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox170
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