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STEM-16. IGF1/N-CADHERIN/b-CATENIN/CLUSTERIN SIGNALING AXIS MEDIATES ADAPTIVE RADIORESISTANCE IN GLIOBLASTOMA

Glioblastoma (GBM) is composed of heterogeneous tumor cell populations including those with stem cell properties, termed glioma stem cells (GSCs). GSCs are innately less radiation sensitive than the tumor bulk and are believed to drive GBM formation and recurrence after repeated irradiation. However...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Osuka, Satoru, Zhu, Dan, Zhang, Zhaobin, Sampetrean, Oltea, Olson, Jeffrey, Saya, Hideyuki, Van Meir, Erwin
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651559/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.833
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