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STEM-16. IGF1/N-CADHERIN/b-CATENIN/CLUSTERIN SIGNALING AXIS MEDIATES ADAPTIVE RADIORESISTANCE IN GLIOBLASTOMA

Glioblastoma (GBM) is composed of heterogeneous tumor cell populations including those with stem cell properties, termed glioma stem cells (GSCs). GSCs are innately less radiation sensitive than the tumor bulk and are believed to drive GBM formation and recurrence after repeated irradiation. However...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Osuka, Satoru, Zhu, Dan, Zhang, Zhaobin, Sampetrean, Oltea, Olson, Jeffrey, Saya, Hideyuki, Van Meir, Erwin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651559/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.833
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