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N-cadherin upregulation mediates adaptive radioresistance in glioblastoma

Glioblastoma (GBM) is composed of heterogeneous tumor cell populations, including those with stem cell properties, termed glioma stem cells (GSCs). GSCs are innately less radiation sensitive than the tumor bulk and are believed to drive GBM formation and recurrence after repeated irradiation. Howeve...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Osuka, Satoru, Zhu, Dan, Zhang, Zhaobin, Li, Chaoxi, Stackhouse, Christian T., Sampetrean, Oltea, Olson, Jeffrey J., Gillespie, G. Yancey, Saya, Hideyuki, Willey, Christopher D., Van Meir, Erwin G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954595/
https://ncbi.nlm.nih.gov/pubmed/33720050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI136098
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