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DDRE-31. EVALUATION OF HIGHLY POTENT AND SELECTIVE SINGLE-MOLECULE DUAL EGFR/PI3K INHIBITORS IN ADULT AND PEDIATRIC HIGH-GRADE GLIOMA

High grade gliomas (HGG) carry poor prognosis with median survival rates under 15 months post diagnosis. Due to dysregulation of kinase signaling pathways within these tumors, targeted kinase inhibition has been considered as a promising clinical strategy. However in HGG, many single-agent inhibitor...

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Bibliografski detalji
Izdano u:Neuro Oncol
Glavni autori: Gangadharan, Achintyan, Sun, Yusha, Bailey, Cavan, Carter, Trever, Espejo, Alexsandra, Whitehead, Christopher, Leopold, Judith, Chandra, Joya
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651413/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.276
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