TAMI-29. MULTIFACTORIAL UPREGULATION OF ID1 DRIVES DIPG INVASIVENESS AND IS THERAPEUTICALLY TARGETABLE

Diffuse intrinsic pontine gliomas (DIPGs) are lethal brain tumors with no effective therapies other than radiation. Inhibitor of DNA binding (ID) proteins, key regulators of lineage commitment during embryogenesis, are implicated in tumorigenesis in multiple human cancers. Prior work showed that rec...

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Опубликовано в: :Neuro Oncol
Главные авторы: Nand Yadav, Viveka, Harris, Micah K, Stallard, Stefanie, Woo, Rinette, Siddaway, Robert, Qin, Tingting, Cummings, Jessica, Mullan, Brendan, Miklja, Zachary, Siada, Ruby, Ravindran, Ramya, Cao, Xuhong, Pasternak, Amy, Castro, Maria G, Lowenstein, Pedro, Mody, Rajen, Chinnaiyan, Arul, Hawkins, Cynthia, Desprez, Pierre, McAllister, Sean, Venneti, Sriram, Koschmann, Carl
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2020
Предметы:
Tumor Microenvironment/Angiogenesis/Metabolism/Invasion
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651395/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.917
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